Scientists reprogram immune cells inside the body to fight cancer

Scientists at UC San Francisco have developed a way to create cancer-fighting CAR-T cells directly inside the body, using a two-particle delivery system to send CRISPR gene-editing tools and new cancer-targeting DNA specifically into T cells, where the DNA was inserted at a precise genomic location. The approach could potentially avoid the slow, extremely expensive process of removing, engineering, and reinfusing a patient's immune cells.

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